Characterization of a novel cell penetrating peptide derived from human Oct4
نویسندگان
چکیده
منابع مشابه
A Novel Cell-Penetrating Peptide Derived from Human Eosinophil Cationic Protein
Cell-penetrating peptides (CPPs) are short peptides which can carry various types of molecules into cells; however, although most CPPs rapidly penetrate cells in vitro, their in vivo tissue-targeting specificities are low. Herein, we describe cell-binding, internalization, and targeting characteristics of a newly identified 10-residue CPP, denoted ECP(32-41), derived from the core heparin-bindi...
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Biomolecules such as proteins, DNA, and RNA are macromolecules and can not cross the cell membrane. However, cell-penetrating peptide (CPP) has been shown to deliver therapeutic biomolecules successfully into cells. The various and widely used CPPs including TAT, VP22, and Antp are mostly non-human originated CPPs, and are limited by their potential toxicity and immunogenicity. We report here o...
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ژورنال
عنوان ژورنال: New Biotechnology
سال: 2014
ISSN: 1871-6784
DOI: 10.1016/j.nbt.2014.05.1627